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What is the dosing requirement of epinephrine for anaphylaxis treatment?

  1. 0.005mg/kg with a maximum of 0.25mg

  2. 0.01mg/kg with a maximum of 0.5mg

  3. 0.02mg/kg with a maximum of 1mg

  4. 0.03mg/kg with a maximum of 2mg

The correct answer is: 0.01mg/kg with a maximum of 0.5mg

Epinephrine is the first line treatment for anaphylaxis, a severe and potentially life-threatening allergic reaction. It is administered through an auto-injector device and the dose depends on the weight of the individual experiencing anaphylaxis. The recommended dosing for epinephrine is 0.01mg/kg of body weight, with a maximum dose of 0.5mg. This means that a person weighing 50kg would receive a dose of 0.5mg, while someone weighing 100kg would receive a maximum dose of 1mg. Option A (0.005mg/kg with a maximum of 0.25mg) is incorrect because it is a lower dose than the recommended 0.01mg/kg, which may not provide enough relief from anaphylaxis symptoms. Option C (0.02mg/kg with a maximum of 1mg) is incorrect because it is a higher dose than the recommended 0.01mg/kg, which may increase the risk of side effects and adverse reactions. Option D (0.03mg/kg with a maximum of 2mg) is incorrect because it is an even higher dose than the incorrect option C, increasing the risk of