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What are the indications of opioid toxicity call?

  1. Altered LOC

  2. Respiratory Depression

  3. Cardiac Arrhythmia

  4. Confusion and Hallucinations

The correct answer is: Altered LOC

Opioid toxicity is characterized by a range of clinical signs, with respiratory depression and altered level of consciousness being among the most significant indicators. Respiratory depression occurs when opioids depress the central nervous system, leading to decreased respiratory drive, which can be life-threatening. While altered level of consciousness can indeed be a sign of opioid toxicity, it is more commonly recognized that respiratory depression is a critical indicator directly associated with the effects of opioid overdose. In many cases, respiratory depression occurs alongside altered consciousness but is a more acute and immediate concern, often requiring urgent intervention. The other signs, such as cardiac arrhythmia, confusion, and hallucinations, can be associated with various conditions but are not primary indicators of opioid toxicity. Their presence may warrant further investigation, but they don't present the same immediate risk as respiratory depression, which demands prompt treatment to prevent severe complications.